A correlation of immunological activity and cellular metabolism of peritoneal exudate cells

摘要: This work was designed to investigate the correlation between immunologic activity and cellular metabolism of peritoneal exudate cells from normal guinea pigs sensitized Lis­ teria monocytogenes. Selected metabolic parameters in nonvirus-infected Newcastle disease virus-infected will also be comparede Studies showed that skin test responses sensi­ tized Listeria monocytogenes were well correlated with macro­ phage migration inhibition using these animals* These assays delayed hypersensitivity indicated attained maximum sensitivity 12 days after inoculation viable Listeria.. comparing oxygen uptake rates state inconclusive; techniques em­ ployed measuring utilization lacked sufficient reproducibil­ ity merit further use. oxidation ^C-l-glucose by significant exists "^CO^ evolution. proved best means correlating meta­ bolic their state. Viral studies revealed marked alterations both induced virus. Possible reasons for relationship expression energy cell-mediated immunity are discussed.