Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity
作者： Maximino Redondo , Teresa Téllez , Maria J Roldan , Alfonso Serrano , Maria García-Aranda
DOI: 10.1186/BCR1835
关键词: Cancer research 、 Cytotoxicity 、 Clusterin 、 Tamoxifen 、 Oncology 、 Breast carcinoma 、 Tumor progression 、 Surgical oncology 、 Breast cancer 、 Chemotherapy 、 Internal medicine 、 Medicine
摘要: Introduction Overexpression of the apoptosis-related protein clusterin is associated with breast cancer development and tumor progression. We describe use clusterin-specific antisense oligonucleotides antibodies to sensitize carcinoma cells anticancer drugs routinely used in therapy.
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