Anti-clusterin antibodies and antigen binding fragments and their use to reduce tumor volume
作者： Traian Sulea , Mario Filion , Gilles Bernard Tremblay
DOI:
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摘要: Novel antibodies and antigen binding fragments that specifically bind to clusterin are described. In some embodiments, the block biological activity of useful in composition certain cancers, more particularly such as endometrial carcinoma, breast hepatocellular prostate a renal cell ovarian pancreatic colorectal carcinoma. The invention also relates cells expressing humanized or hybrid antibodies. Additionally, methods detecting treating cancer using disclosed.
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