Salvage of isolated vaginal recurrences in women with surgical stage I endometrial cancer: a multiinstitutional experience.
作者： W.K. HUH , J.M. STRAUGHN , A. MARIANI , K. C. PODRATZ , L.J. HAVRILESKY
DOI: 10.1111/J.1525-1438.2007.00858.X
关键词: Dissection 、 Endometrial cancer 、 Hysterectomy 、 Lymph node 、 Medicine 、 Abdomen 、 Adjuvant therapy 、 Surgery 、 Radiation therapy 、 Stage (cooking)
摘要: The objective of this study was to evaluate the treatment outcomes and risk factors women with surgical stage I endometrial adenocarcinoma who were initially treated surgery alone subsequently developed isolated vaginal recurrences. Patients diagnosed from 1975 2002 identified tumor registry databases at seven institutions. All patients including a total hysterectomy, bilateral salpingo-oophorectomy, pelvic (+/− para-aortic) lymph node dissection, peritoneal cytology did not receive postoperative radiation therapy. Vaginal recurrences documented histologically. Metastatic disease in chest abdomen excluded by radiologic studies. Overall survival calculated Kaplan–Meier method. Sixty-nine cancer identified. Of 69 patients, 10 (15%) IA disease, 43 (62%) IB 16 (23%) IC disease. grade 1 22 (32%), 2 26 (38%), 3 21 (30%). Among women, 81% salvaged mean time recurrence 24 months, follow-up 63 months. 18% died subsequent recurrent 5-year overall 75%. majority can be successfully therapy, further questioning role adjuvant therapy for uterine-confined initial diagnosis
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