Poly-cyclodextrin and poly-paclitaxel nano-assembly for anticancer therapy
作者： Ran Namgung , Yeong Mi Lee , Jihoon Kim , Yuna Jang , Byung-Heon Lee
DOI: 10.1038/NCOMMS4702
关键词: Paclitaxel 、 Polymer 、 Combinatorial chemistry 、 Chemistry 、 In vivo 、 Nano- 、 Cyclodextrin 、 Reduction Activity 、 Pharmacology 、 Conjugate
摘要: Effective anticancer therapy can be achieved by designing a targeted drug-delivery system with high stability during circulation and efficient uptake by the target tumour cancer cells. We …
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A. Ruebner, D. Kirsch, S. Andrees, W. Decker, B. Roeder, B. Spengler, R. Kaufmann, J.G. Moser, DIMERIC CYCLODEXTRIN CARRIERS WITH HIGH BINDING AFFINITY TO PORPHYRINOID PHOTOSENSITIZERS Journal of inclusion phenomena and molecular recognition in chemistry. ,vol. 27, pp. 69- 84 ,(1997) , 10.1023/A:1007942308945
Joerg G. Moser, Irene Rose, Birgit Wagner, Tim Wieneke, Anja Vervoorts, Taxol Inclusion Complexes with a Cyclodextrin Dimer: Possibilities to Detoxify Chemotherapeutics and to Target Drugs Specifically to Tumors? Journal of Inclusion Phenomena and Macrocyclic Chemistry. ,vol. 39, pp. 13- 18 ,(2001) , 10.1023/A:1008114826524
P. Leland, J. Taguchi, S. R. Husain, R. J. Kreitman, I. Pastan, R. K. Puri, Human breast carcinoma cells express type II IL-4 receptors and are sensitive to antitumor activity of a chimeric IL-4-Pseudomonas exotoxin fusion protein in vitro and in vivo. Molecular Medicine. ,vol. 6, pp. 165- 178 ,(2000) , 10.1007/BF03402112
Mary Ann Jordan, Leslie Wilson, Microtubules as a target for anticancer drugs. Nature Reviews Cancer. ,vol. 4, pp. 253- 265 ,(2004) , 10.1038/NRC1317
Hiroshi Maeda, Minoru Ueda, Tetsuo Morinaga, Tomonori Matsumoto, Conjugation of poly(styrene-co-maleic acid) derivatives to the antitumor protein neocarzinostatin: pronounced improvements in pharmacological properties Journal of Medicinal Chemistry. ,vol. 28, pp. 455- 461 ,(1985) , 10.1021/JM00382A012
Ying Wang, Dingcheng Xin, Kaijian Liu, Mingqiang Zhu, Jiannan Xiang, Heparin-paclitaxel conjugates as drug delivery system: synthesis, self-assembly property, drug release, and antitumor activity. Bioconjugate Chemistry. ,vol. 20, pp. 2214- 2221 ,(2009) , 10.1021/BC8003809
G. Cavallaro, M. Licciardi, P. Caliceti, S. Salmaso, G. Giammona, Synthesis, physico-chemical and biological characterization of a paclitaxel macromolecular prodrug. European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 58, pp. 151- 159 ,(2004) , 10.1016/J.EJPB.2004.02.012
Aurélia Charlot, Rachel Auzély-Velty, Synthesis of Novel Supramolecular Assemblies Based on Hyaluronic Acid Derivatives Bearing Bivalent β-Cyclodextrin and Adamantane Moieties Macromolecules. ,vol. 40, pp. 1147- 1158 ,(2007) , 10.1021/MA062322E
Hiroshi Maeda, SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy. Advanced Drug Delivery Reviews. ,vol. 46, pp. 169- 185 ,(1991) , 10.1016/S0169-409X(00)00134-4
Jae Og Jeon, Soyoun Kim, Eunsu Choi, Kihyuk Shin, Kiweon Cha, In-Seop So, Sun-Ji Kim, Eunsung Jun, Dohee Kim, Hyung Jun Ahn, Byung-Heon Lee, Seung-Hyo Lee, In-San Kim, Designed nanocage displaying ligand-specific Peptide bunches for high affinity and biological activity. ACS Nano. ,vol. 7, pp. 7462- 7471 ,(2013) , 10.1021/NN403184U