Conversion of [1-3H2,G-14C]geranyl pyrophosphate to cyclic monoterpenes without loss of tritium
作者： Rodney Croteau , Mark Felton
DOI: 10.1016/0003-9861(81)90054-0
关键词: Limonene 、 Monoterpene 、 Geraniol 、 Bornane 、 Salvia officinalis 、 Geranyl pyrophosphate 、 Camphor 、 Camphene 、 Chemistry 、 Organic chemistry
摘要: Abstract Soluble enzyme preparations from Salvia officinalis convert the acyclic precursor [1- 3 H 2 ,G- 14 C]geranyl pyrophosphate to cyclic monoterpenes of pinane (α-pinene,β-pinene), isocamphane (camphene), p -menthane (limonene,1,8-cineole), and bornane (bornyl pyrophosphate, determined as borneol) type without loss tritium, significant conversion other free intermediates. Similarly, C]geraniol is converted in intact S. leaves monoterpene olefins 1,8-cineole, well isothujone camphor, tritium C(1). These results clearly eliminate transcis isomerization geranyl neryl via aldehyde intermediates prior cyclization, they support a scheme whereby trans cyclized directly by way bound linaloyl intermediate.
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