Non enzymic formation of nerolidol from farnesyl pyrophosphate in the presence of bivalent cations
作者： C. George-Nascimento , R. Pont-Lezica , O. Cori
DOI: 10.1016/0006-291X(71)90058-1
关键词: Farnesyl pyrophosphate 、 Terpenoid 、 Magnesium 、 Farnesol 、 Stereochemistry 、 Mevalonic acid 、 Hydrolysis 、 Nerolidol 、 Chemistry 、 Terpene 、 Biophysics 、 Cell biology 、 Biochemistry 、 Molecular biology
摘要: Abstract 1-3H Farnesyl pyrophosphate is hydrolyzed non enzymically at neutral or alkaline pH in the presence of Mg2+ Mn2+. The pattern product formation differs for these two ions. In Mn2+, nerolidol practically only reaction product, whereas hydrolysis products are and farnesols. effect dependent. from mevalonic acid other precursors isoprenoids may thus be explained as a enzymic farnesyl pyrophosphate.
elsevier.com
sci-hub.se 参考文章(13)
G Popják, J Edmond, K Clifford, V Williams, Biosynthesis and structure of a new intermediate between farnesyl pyrophosphate and squalene. Journal of Biological Chemistry. ,vol. 244, pp. 1897- 1918 ,(1969) , 10.1016/S0021-9258(18)91765-5
F. Cramer, W. Rittersdorf, Die hydrolyse von phosphaten und pyrophosphaten einiger monoterpenalkohole Tetrahedron. ,vol. 23, pp. 3015- 3022 ,(1967) , 10.1016/S0040-4020(01)83356-1
R. B. Bates, D. M. Gale, B. J. Gruner, The Stereoisomeric Farnesols1 Journal of Organic Chemistry. ,vol. 28, pp. 1086- 1089 ,(1963) , 10.1021/JO01039A054
Enrique Beytía, Pablo Valenzuela, Osvaldo Cori, Terpene biosynthesis: Formation of nerol, geraniol, and other prenols by an enzyme system from Pinus radiata seedlings Archives of Biochemistry and Biophysics. ,vol. 129, pp. 346- 356 ,(1969) , 10.1016/0003-9861(69)90185-4
John A. Attaway, Arthur P. Pieringer, Leonard J. Barabas, The origin of citrus flavor components—III.: A study of the percentage variations in peel and leaf oil terpenes during one season☆ Phytochemistry. ,vol. 6, pp. 25- 32 ,(1967) , 10.1016/0031-9422(67)85004-0
V.H. Potty, auJ.H. Bruemmer, Formation of isoprenoid pyrophosphates from mevalonate by orange enzymes Phytochemistry. ,vol. 9, pp. 1229- 1237 ,(1970) , 10.1016/S0031-9422(00)85313-3
R VANALLER, W NES, The phosphorylation of geraniol in germinating peas☆ Phytochemistry. ,vol. 7, pp. 85- 88 ,(1968) , 10.1016/S0031-9422(00)88210-2
L. Ruzicka, The isoprene rule and the biogenesis of terpenic compounds. Cellular and Molecular Life Sciences. ,vol. 9, pp. 357- 367 ,(1953) , 10.1007/BF02167631
C. George-Nascimento, O. Cori, Terpene biosynthesis from geranyl and neryl pyrophosphates by enzymes from orange flavedo Phytochemistry. ,vol. 10, pp. 1803- 1810 ,(1971) , 10.1016/S0031-9422(00)86441-9
F. Lynen, H. Eggerer, U. Henning, Ingrid Kessel, Farnesyl-pyrophosphat und 3-Methyl-Δ3-butenyl-1-pyrophosphat, die biologischen Vorstufen des Squalens. Zur Biosynthese der Terpene, III Angewandte Chemie. ,vol. 70, pp. 738- 742 ,(1958) , 10.1002/ANGE.19580702403