Deposition behavior and properties of silk fibroin scaffolds soaked in simulated body fluid
作者： Feng Lin , Yucheng Li , Jun Jin , Yurong Cai , Kemin Wei
DOI: 10.1016/J.MATCHEMPHYS.2008.03.019
关键词: Biocompatibility 、 Thermal stability 、 Composite material 、 Chemical engineering 、 Porosity 、 Simulated body fluid 、 Fibroin 、 Materials science 、 Fourier transform infrared spectroscopy 、 Polymer 、 Glutaraldehyde 、 General Materials Science 、 Condensed matter physics
摘要: Abstract Porous 3D silk fibroin (SF) scaffolds were prepared directly from the SF solution with addition of methanol and glutaraldehyde by a freeze-drying method. The then soaked in simulated body fluid (SBF) for deposition hydroxyapatite (HA) crystals. XRD FTIR results showed that β-sheet structure, resulting high thermal stability mechanical properties scaffolds. AAS data revealed could induce continuous growth enrichment HA crystals onto extension soaking time. increased first HA-deposition within 3 d soaking, it declined. During full period, no significant change was observed on porosity water-binding ability, which kept at about 84% 800%, respectively. cell cultivation have satisfied biocompatibility, promoted after HA-deposition. This work suggests porous may be potential candidate bone engineering.
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