作者: V.M. Correlo , J.M. Oliveira , J.F. Mano , N.M. Neves , R.L. Reis
DOI: 10.1016/B978-0-12-381422-7.10032-X
关键词: Blowing agent 、 Thermoplastic 、 Compression molding 、 Porosity 、 Starch 、 Materials science 、 Chitosan 、 Spinning 、 Composite material 、 Extrusion
摘要: This chapter focuses on properties, processing, and performance of natural origin materials employed for bone tissue engineering. One the is starch, a predominant energy-storing compound in many plants. Due to thermoplastic behavior starch-based blends composites, it possible produce 3D porous scaffolds using traditional melt-based technologies, such as compression molding combined with particulate leaching, injection or extrusion blowing agents. The two types produced by this method exhibit typical fiber-mesh structure, fiber diameter approximately 180 μm SPCL 210 SPLA, highly interconnected pores porosity 75%. Another material chitosan, homopolymer β (1→4)-linked N -acetyl-D-glucosamine residues. A very interesting property chitosan that can be transformed into structures high degree interconnectivity various technologies; example, lyophilizing frozen solution powder dissolved acetic acid. obtained have porosities ∼ 80% median pore diameters 68 μm. mean controlled within range 1-250 varying freezing conditions. Wet spinning one most used methods fibers has been prepare meshes. an average size 100-500 μm, which ideal bone-related applications.