Pregnancy after pancreas-kidney transplantation.

摘要: A combined kidney and pancreas transplant is a therapeutic option for patients with type 1 diabetes end-stage renal disease. After successful transplantation, fertility rapidly restored, allowing women of childbearing age to have spontaneous pregnancies men father pregnancies. These are at increased risk maternal neonatal adverse outcomes due immunosuppressive therapy, comorbidities, previous surgery, although the majority ends birth live healthy offspring. Hypertension, miscarriages, diabetes, infections, graft rejections, preterm delivery low weight may complicate after pancreas-kidney transplantation. Since not all drugs can be safely used in pregnancy, it important review treatment before conception. Adequate pre-conception counseling inform their partners about potential risks pregnancy grafts advantages planning. should managed within multidisciplinary team, comprising physician, an endocrinologist, nephrologist, obstetrician neonatologist. Last but least, very continue collecting data on transplantation aim improve knowledge generate evidence-based guidelines care transplants who considering pregnancy.