Strategies for the Recruitment and Retention of Racial/Ethnic Minorities in Alzheimer Disease and Dementia Clinical Research

摘要: Background Racial/ethnic minorities have among the highest risks for Alzheimer disease and dementia, but remain underrepresented in clinical research studies. Objective To synthesize current evidence on strategies to recruit retain racial/ethnic dementia research. Methods We conducted a systematic review by searching CINAHL, EMBASE, MEDLINE, PsycINFO, Scopus. included studies that met four criteria: (1) minority group (African American, Latino, Asian, American Indian or Alaska Native, Native Hawaiian Other Pacific Islander); (2) implemented recruitment retention strategy research; (3) within U.S.; (4) published peer-reviewed journal. Results Of 19 studies, 14 (73.7%) 5 (26.3%) both strategies. Fifteen (78.9%) focused African Americans, two (10.6%) Americans Latinos, (10.5%) Asians. All articles were rated weak study quality. Four major themes identified strategies: community outreach (94.7%), advertisement (57.9%), collaboration with health care providers (42.1%), referral (21.1%). Three follow-up communication (15.8%), maintain relationship convenience (10.5%). Conclusion Our findings highlight several promising investigators should prioritize when allocating limited resources, however, additional well-designed are needed. By recruiting retaining more research, may better understand heterogeneity of progression marginalized groups. PROSPERO registration #CRD42018081979.