Supramolecular Synthesis of 3-Indolyl-3-hydroxy Oxindoles under Neutral Conditions in Water

作者: V. Pavan Kumar , V. Prakash Reddy , R. Sridhar , B. Srinivas , M. Narender

DOI: 10.1021/JO702496S

关键词: IsatinChemistryLactamCyclodextrinChemical synthesisCatalysisSupramolecular chemistrySupramolecular catalysisOrganic chemistryInclusion compound

摘要: Various 3-indolyl-3-hydroxy oxindoles were prepared for the first time by supramolecular catalysis involving reaction of beta-CD:isatin complexes with indoles under neutral conditions in water. beta-Cyclodextrin can be recovered and reused a number times without loss activity.

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