Anti-psgl-1 antibodies

作者: Chung Nan Chang , Pei-Jiun Chen , Chiu-Chen Huang , Rong-Hwa Lin

DOI:

关键词: Immune systemComplementarity determining regionAntibodyHeavy chainPrimary and secondary antibodiesBiologyGlycoproteinImmunologyVirology

摘要: Immunoglobulin chains or antibodies having light heavy chain complementarity determining regions of that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are methods inducing death an activated T-cell and modulating a T cell-mediated immune response in subject.

参考文章(78)
Daqing W. Hartwell, Patrick Andre, Denisa D. Wagner, Ingrid Hrachovinova, Methods of treating hemophilia or von willebrand disease with p-selectin ,(2004)
Francis W. Luscinskas, Geoffrey S. Kansas, Karen R. Snapp, Han Ding, Kristin Atkins, Roger Warnke, A Novel P-Selectin Glycoprotein Ligand-1 Monoclonal Antibody Recognizes an Epitope Within the Tyrosine Sulfate Motif of Human PSGL-1 and Blocks Recognition of Both P- and L-Selectin Blood. ,vol. 91, pp. 154- 164 ,(1998) , 10.1182/BLOOD.V91.1.154
Virgilio Evangelista, Stefano Manarini, Rita Sideri, Serenella Rotondo, Nicola Martelli, Antonio Piccoli, Licia Totani, Paola Piccardoni, Dietmar Vestweber, Giovanni de Gaetano, Chiara Cerletti, Platelet/Polymorphonuclear Leukocyte Interaction: P-Selectin Triggers Protein-Tyrosine Phosphorylation–Dependent CD11b/CD18 Adhesion: Role of PSGL-1 as a Signaling Molecule Blood. ,vol. 93, pp. 876- 885 ,(1999) , 10.1182/BLOOD.V93.3.876
Daming Shan, Jeffrey A. Ledbetter, Oliver W. Press, Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies Blood. ,vol. 91, pp. 1644- 1652 ,(1998) , 10.1182/BLOOD.V91.5.1644
Pei Wu, Xiao Li, Tong Zhou, Ming Jun Zhang, Jin Lian Chen, Wei Ming Wang, Nan Chen, None, Role of P-selectin and anti-P-selectin monoclonal antibody in apoptosis during hepatic/renal ischemia-reperfusion injury World Journal of Gastroenterology. ,vol. 6, pp. 244- 247 ,(2000) , 10.3748/WJG.V6.I2.244
Stephen Paul Cobbold, Herman Waldmann, Non-depleting anti-CD4 monoclonal antibodies and tolerance induction ,(1995)
Tadayuki Yago, Mutsuhiko Minami, Mamoru Tsukuda, Tatsunari Nishi, Hideyuki Yamaoka, Hirofumi Fukushima, Kazumi Kurata-Miura, IL-12 Promotes the Adhesion of NK Cells to Endothelial Selectins Under Flow Conditions Journal of Immunology. ,vol. 161, pp. 1140- 1145 ,(1998)
David V. Serreze, Luciano Adorini, Silvia Gregori, Giuseppe Penna, Jeanne Magram, Sylvie Trembleau, Harold D. Chapman, Pancreas-Infiltrating Th1 Cells and Diabetes Develop in IL-12-Deficient Nonobese Diabetic Mice Journal of Immunology. ,vol. 163, pp. 2960- 2968 ,(1999)
Robert Rothlein, Paul C. Harrison, Jeffrey B. Madwed, Takashi Kei Kishimoto, Combination anti-selectin and immunosuppressant therapy ,(1999)