An Overview on: Sublingual Route for Systemic Drug Delivery

摘要: Oral mucosal drug delivery is an alternative and promising method of systemic which offers several advantages. Sublingual literally meaning ''under the tongue'', administrating substance via mouth in such a way that rapidly absorbed blood vessels under tongue. route advantages as bypasses hepatic first pass metabolic process gives better bioavailability, rapid onset action, patient compliance , self-medicated. Dysphagia (difficulty swallowing) common among all ages people more pediatric, geriatric, psychiatric patients. In terms permeability, sublingual area oral cavity permeable than buccal turn palatal area. Different techniques are used to formulate dosage forms. administration applied field cardiovascular drugs, steroids, enzymes some barbiturates. This review highlights advantages, disadvantages, different formulation tablets films, evaluation.