Oral local drug delivery: An overview

作者: Anoop Kurian Mathew

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摘要: Oral cavity is a site where both local and systemic delivery of drugs can take place. route has been the most convenient commonly employed drug delivery. mucosal an alternative promising method which offers several advantages. Local allows topical treatment various oral diseases. However, be made effective if targeted directly to lesion, thereby reducing side effects. This review mainly focuses on mucosa, its structure permeability features, routes important aspects mucoadhesive delivery, dosage forms for lesions.

参考文章(9)
Amir H. Shojaei, Buccal mucosa as a route for systemic drug delivery: a review. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences. ,vol. 1, pp. 15- 30 ,(1998)
Mohit Tripathi, Rakesh Hooda, Kiran Kapoor, A Review on Oral Mucosal Drug Delivery System The Pharma Innovation Journal. ,vol. 1, pp. 14- 21 ,(2012)
Jie Liu, Xin Zeng, Qianming Chen, Yang Cai, Fangchun Chen, Yan Wang, Hongmei Zhou, Mei Lin, Jing Shi, Zhi Wang, Yuanyuan Zhang, An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. ,vol. 102, pp. 475- 481 ,(2006) , 10.1016/J.TRIPLEO.2005.12.014
Viralkumar F. Patel, Fang Liu, Marc B. Brown, Advances in oral transmucosal drug delivery. Journal of Controlled Release. ,vol. 153, pp. 106- 116 ,(2011) , 10.1016/J.JCONREL.2011.01.027
Carlo Paderni, Domenico Compilato, Libero Italo Giannola, Giuseppina Campisi, Oral local drug delivery and new perspectives in oral drug formulation Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. ,vol. 114, pp. e25- e34 ,(2012) , 10.1016/J.OOOO.2012.02.016
Beatrice Gandera, Takashi Fujibayashi, Mahvash Navazesh, Nelson L. Rhodus, Morten Schiødt, Inger von Bültzingslöwen, Thomas P. Sollecito, Philip C. Fox, Troy Daniels, Roland Jonsson, Peter B. Lockhart, David Wray, Michael T. Brennan, Marco Carrozzo, Salivary dysfunction associated with systemic diseases: systematic review and clinical management recommendations. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology. ,vol. 103, pp. 1- 15 ,(2007) , 10.1016/J.TRIPLEO.2006.11.010
Shri Baba, Neha Narang, Jyoti Sharma, SUBLINGUAL MUCOSA AS A ROUTE FOR SYSTEMIC DRUG DELIVERY ,(2011)