An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial
作者： Jie Liu , Xin Zeng , Qianming Chen , Yang Cai , Fangchun Chen
DOI: 10.1016/J.TRIPLEO.2005.12.014
关键词: Cohort 、 Erythema 、 Amlexanox 、 Pain scale 、 Randomized controlled trial 、 Internal medicine 、 aphthous ulcer 、 Surgery 、 Cohort study 、 Medicine 、 Clinical trial 、 Oral surgery 、 Otorhinolaryngology 、 General Dentistry
摘要: Objective The objectives of this study were to clinically determine the topical efficacy and safety amlexanox oral adhesive tablets in treatment recurrent minor aphthous ulcerations (MiRAU) a Chinese cohort. Study design A randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial was carried out. applied by subjects themselves 4 times day for 5 days. Four parameters (pain scale, size change, degree erythema exudation, index) recorded both before (baseline) during (on morning days 6). Results There 104 108 who fulfilled group vehicle-control group, respectively. Group differences all but exudation statistically significant visit 6 ( P Conclusions Amlexanox are effective safe reducing ulcer pain lesion size, as well
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