ERK activation upon hypoxia: involvement in HIF-1 activation
作者： E Minet , T Arnould , G Michel , I Roland , D Mottet
DOI: 10.1016/S0014-5793(00)01181-9
关键词: Phosphorylation 、 Biology 、 Cell biology 、 Transactivation 、 Transcription factor 、 Mitogen-Activated Protein Kinase 3 、 Kinase 、 Hypoxia (medical) 、 Protein kinase A 、 MAPK/ERK pathway
摘要: … and their involvement in HIF-1 activation. We … HIF-1 transactivation activity. Moreover, using a kinase assay and Western blot experiments, we showed that HIF-1α is phosphorylated in …
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