Modification of photocarcinogenesis by two immunosuppressive agents
作者： Robert B. Nathanson , P. Donald Forbes , Frederick Urbach
DOI: 10.1016/S0304-3835(75)97305-X
关键词: Daily exposure 、 Cancer research 、 Multiple tumors 、 Ultraviolet radiation 、 Carcinogen 、 Medicine 、 Immunology 、 Hairless 、 Carcinogenesis 、 Oncology
摘要: Summary The carcinogenic effect of ultraviolet radiation (UVR) on the skin hairless (hr) mice was modified by two immunosuppressive agents, rabbit anti-mouse lymphocytic serum (ALS), and 6-mercaptopurine (6MP). Daily exposure to UVR resulted in multiple tumor production. Carcinogenesis measured terms affected (prevalence) numbers tumors produced. By both criteria, photocarcinogenesis enhanced ALS but inhibited 6MP.
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