Synthetic biology approaches to engineer T cells
作者： Chia-Yung Wu , Levi J Rupp , Kole T Roybal , Wendell A Lim
DOI: 10.1016/J.COI.2015.06.015
关键词: T cell 、 Synthetic biology 、 Immune system 、 Biotechnology 、 Computational biology 、 Extramural 、 Neoplasms therapy 、 Cancer cell 、 Computer science
摘要: There is rapidly growing interest in learning how to engineer immune cells, such as T lymphocytes, because of the potential these engineered cells be used for therapeutic applications recognition and killing cancer cells. At same time, our knowhow capability logically cellular behavior with development synthetic biology. Here we describe biology approaches are being rationally alter optimize them functions. We also future developments that will important order construct safe precise cell therapeutics.
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