Enhancement of Immune Response in Mice Fed with Streptococcus thermophilus and Lactobacillus acidophilus

作者: G. Perdigon , M.E. Nader de Macias , S. Alvarez , G. Oliver , A.A. Pesce de Ruiz Holgado

DOI: 10.3168/JDS.S0022-0302(87)80095-4

关键词: StreptococcaceaeImmune systemMononuclear phagocyte systemCellular immunityStreptococcus thermophilusBiologyMicrobiologyLactobacillus acidophilusLymphocyteLactic acid

摘要: Swiss mice, fed for 8 consecutive d with 50 micrograms/d of viable cultures Lactobacillus acidophilus and Streptococcus thermophilus, showed significant variation in their immune system. In order to study this phenomenon assays macrophage lymphocyte function were carried out. Both lactic acid bacteria enhanced significantly the enzymatic phagocytic activity peritoneal macrophages as checked against controls also accelerated reticuloendothelial system revealed by carbon clearance test. On 2nd (100 micrograms), L. reached a peak K = .271, which remained high. thermophilus was effective only on then decreased. The lymphocytic studied immunoglobulin secreting cells assayed Jerne's method plaque-forming (PFC). This increased two microorganisms. proved more than acidophilus. S. activated lymphocytes produced same increase response mice whether administered orally or intraperitoneally.

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