Structure and relaxation properties of medical-purposed polyacrylamide gels

摘要: By IR and NMR spectroscopy methods, thermomechanical analysis, mechanical relaxation measurements, computational simulation the effect of production conditions acrylamide copolymer N,N′-methylenebisacrylamide derived hydrogels with respect to their properties were studied. Four hydrogel samples, prepared under different (γ-radiation dose autoclaving), investigated. It was found that autoclaving γ-radiation lead a slight increase crosslinking degree in polymeric network formation alkene structures chains. Stress creep processes axial compression gel cylindrical samples studied detail. To approximate stress curves new memory functions used, based on analysis entropy system during process. primary initial gels induces an quasi-equilibrium rubbery elasticity modulus, compliance is decreased. The opposite situation observed further at 120°C. After autoclaving, required sterilize gels, treatment by again induced noticeable modulus decrease. mechanism be associated limiting stage physical interaction between relaxants, representing micro-inhomogeneities material. investigation results compared data obtained histology morphology methods. A additional did not swell when implanted into living organism, tissue reaction implantation such minimal. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 96: 1043–1058,