Subversion of cell cycle regulatory pathways.
作者： V. Sanchez , D. H. Spector
DOI: 10.1007/978-3-540-77349-8_14
关键词: Apoptosis 、 Cell cycle checkpoint 、 Virus 、 Herpesviridae 、 Cell cycle 、 Congenital cytomegalovirus infection 、 Biology 、 Virology 、 Origin recognition complex 、 Human cytomegalovirus
摘要: Human cytomegalovirus (HCMV) has evolved numerous strategies to commandeer the host cell for producing viral progeny. The virus manipulates cycle pathways from early stages of infection stimulate DNA replication at expense cellular synthesis. At same time, checkpoints are by-passed, preventing apoptosis and allowing sufficient time assembly infectious virus.
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