作者: Martin Cvek , Miroslav Mrlík , Markéta Ilčíková , Jaroslav Mosnáček , Vladimir Babayan
DOI: 10.1039/C5RA11968E
关键词: Polymer chemistry 、 Chemical engineering 、 Silicone oil 、 Glycidyl methacrylate 、 Yield (engineering) 、 Rheology 、 Shear rate 、 Atom-transfer radical-polymerization 、 Carbonyl iron 、 Materials science 、 Chemical stability
摘要: Carbonyl iron (CI) particles were grafted with poly(glycidyl methacrylate) (PGMA) using atom transfer radical polymerization. Compact coating of PGMA largely improved the chemical stability in an acid environment and thus reduced common drawback bare CI particles. Furthermore, due to possible medical applications CI-polymer systems for magnetic drug targeting, vitro cytotoxicity test was performed NIH/3T3 cell line. The viability evaluated by spectrometric assay (MTT). results show that prepared are not cytotoxic. Moreover, as well synthesized core–shell suspended silicone oil, rheological behavior MR suspensions investigated controlled shear rate mode under various field strengths. Dynamic yield stress a measure rigidity created internal structures determined Herschel–Bulkley model, which provided reasonably good fit data. PGMA-coated exhibited only slightly decreased stresses their negligibly-affected performance.