The chemical stability and cytotoxicity of carbonyl iron particles grafted with poly(glycidyl methacrylate) and the magnetorheological activity of their suspensions

作者: Martin Cvek , Miroslav Mrlík , Markéta ​Ilčíková , Jaroslav Mosnáček , Vladimir Babayan

DOI: 10.1039/C5RA11968E

关键词: Polymer chemistryChemical engineeringSilicone oilGlycidyl methacrylateYield (engineering)RheologyShear rateAtom-transfer radical-polymerizationCarbonyl ironMaterials scienceChemical stability

摘要: Carbonyl iron (CI) particles were grafted with poly(glycidyl methacrylate) (PGMA) using atom transfer radical polymerization. Compact coating of PGMA largely improved the chemical stability in an acid environment and thus reduced common drawback bare CI particles. Furthermore, due to possible medical applications CI-polymer systems for magnetic drug targeting, vitro cytotoxicity test was performed NIH/3T3 cell line. The viability evaluated by spectrometric assay (MTT). results show that prepared are not cytotoxic. Moreover, as well synthesized core–shell suspended silicone oil, rheological behavior MR suspensions investigated controlled shear rate mode under various field strengths. Dynamic yield stress a measure rigidity created internal structures determined Herschel–Bulkley model, which provided reasonably good fit data. PGMA-coated exhibited only slightly decreased stresses their negligibly-affected performance.

参考文章(47)
Carolyn L. Bayer, Isis J. Trenchard, Nicholas A. Peppas, Analyzing polyaniline-poly(2-acrylamido-2-methylpropane sulfonic acid) biocompatibility with 3T3 fibroblasts. Journal of Biomaterials Science-polymer Edition. ,vol. 21, pp. 623- 634 ,(2010) , 10.1163/156856209X434647
S. G. Belyavskii, P. G. Mingalyov, F. Giulieri, R. Combarrieau, G. V. Lisichkin, Chemical modification of the surface of a carbonyl iron powder Protection of Metals. ,vol. 42, pp. 244- 252 ,(2006) , 10.1134/S0033173206030064
Joko Sutrisno, Alan Fuchs, Huseyin Sahin, Faramarz Gordaninejad, Surface coated iron particles via atom transfer radical polymerization for thermal-oxidatively stable high viscosity magnetorheological fluid Journal of Applied Polymer Science. ,vol. 128, pp. 470- 480 ,(2013) , 10.1002/APP.38199
Martin Cvek, Miroslav Mrlik, Marketa Ilcikova, Tomas Plachy, Michal Sedlacik, Jaroslav Mosnacek, Vladimir Pavlinek, A facile controllable coating of carbonyl iron particles with poly(glycidyl methacrylate): a tool for adjusting MR response and stability properties Journal of Materials Chemistry C. ,vol. 3, pp. 4646- 4656 ,(2015) , 10.1039/C5TC00319A
Pedro Francisco Cañamero, José Luis de la Fuente, Enrique López Madruga, Marta Fernández-García, Atom Transfer Radical Polymerization of Glycidyl Methacrylate: A Functional Monomer Macromolecular Chemistry and Physics. ,vol. 205, pp. 2221- 2228 ,(2004) , 10.1002/MACP.200400186
Gil Gonçalves, Paula AAP Marques, Ana Barros-Timmons, Igor Bdkin, Manoj K Singh, Nazanin Emami, José Grácio, None, Graphene oxide modified with PMMA via ATRP as a reinforcement filler Journal of Materials Chemistry. ,vol. 20, pp. 9927- 9934 ,(2010) , 10.1039/C0JM01674H
M. Sedlacik, V. Pavlinek, A tensiometric study of magnetorheological suspensions' stability RSC Advances. ,vol. 4, pp. 58377- 58385 ,(2014) , 10.1039/C4RA11842A
W. Kordonski, A. Shorey, Magnetorheological (MR) Jet Finishing Technology Journal of Intelligent Material Systems and Structures. ,vol. 18, pp. 1127- 1130 ,(2007) , 10.1177/1045389X07083139
M Sedlacik, V Pavlinek, R Vyroubal, P Peer, P Filip, A dimorphic magnetorheological fluid with improved oxidation and chemical stability under oscillatory shear Smart Materials and Structures. ,vol. 22, pp. 035011- ,(2013) , 10.1088/0964-1726/22/3/035011