Electronic Role of 3-Iminophosphine Ligands in Palladium-Catalyzed Intermolecular Hydroamination
作者： Hosein Tafazolian , Danielle C. Samblanet , Joseph A. R. Schmidt
DOI: 10.1021/OM500792K
关键词: Imine 、 Combinatorial chemistry 、 Moiety 、 Catalytic cycle 、 Organic chemistry 、 Ligand 、 Chemistry 、 Hydroamination 、 Trifluoromethanesulfonate 、 Palladium 、 Catalysis
摘要: This study of the electronic characteristics (3-iminophosphine)allylpalladium triflate complexes has yielded catalysts with moderate to high activity for hydroamination monosubstituted allenes utilizing a wide range amines. Herein, new series these was synthesized by varying group on imine moiety in order explore effect electronics ligand’s catalytic intermolecular reactions. Four amine substrates were examined cyclohexylallene, and apparent first-order rate constants obtained 1H NMR spectroscopy. Kinetic isotope studies also performed support proposed cycle cyclohexylallene secondary amines using [(3IP)Pd(allyl)]OTf catalysts.
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