Association of Monocyte Chemoattractant Protein‐1 (MCP‐1)‐2518A>G Polymorphism with Susceptibility to Coronary Artery Disease: A Meta‐Analysis
作者： Xiao-Yan Bai , Shujing Li , Miao Wang , Xinjian Qu , Gaolei Hu
DOI: 10.1111/AHG.12105
关键词: Genetic model 、 Oncology 、 Coronary artery disease 、 Meta-analysis 、 Monocyte 、 Medicine 、 Confidence interval 、 Internal medicine 、 Population 、 Bioinformatics 、 Odds ratio 、 Monocyte chemoattractant protein
摘要: Summary We attempted to systematically elucidate the association between monocyte chemoattractant protein-1 (MCP-1) -2518A>G polymorphism and risk of coronary artery disease (CAD). Eligible studies were identified through PubMed, EBSCO, Web Science Databases. The magnitude MCP-1 effect its possible mode action on CAD estimated. odds ratio (OR) with 95% confidence intervals (CI) pooled in a specific genetic model assess association. A total 21 involved. There was significant gene overall population (likelihood test: p G may be associated susceptibility CAD, especially Caucasians.
sci-hub.se 参考文章(54)
Chao Xuan, Li-Min Lun, Jin-Xia Zhao, Hong-Wei Wang, Bao-Zhi Zhu, Shui Yu, Zhen Liu, Guo-Wei He, PTPN22 Gene Polymorphism (C1858T) Is Associated with Susceptibility to Type 1 Diabetes: A Meta‐Analysis of 19,495 Cases and 25,341 Controls Annals of Human Genetics. ,vol. 77, pp. 191- 203 ,(2013) , 10.1111/AHG.12016
Colin B. Begg, Madhuchhanda Mazumdar, Operating characteristics of a rank correlation test for publication bias. Biometrics. ,vol. 50, pp. 1088- 1101 ,(1994) , 10.2307/2533446
Hongming Pan, Wenquan Niu, Lan He, Bin Wang, Jun Cao, Feng Zhao, Ying Liu, Shen Li, Huijian Wu, Contributory Role of Five Common Polymorphisms of RAGE and APE1 Genes in Lung Cancer among Han Chinese PLoS ONE. ,vol. 8, pp. e69018- ,(2013) , 10.1371/JOURNAL.PONE.0069018
Ramandeep Kaur, Kawaljit Matharoo, Punit Arora, A.J.S. Bhanwer, Association of −2518A>G Promoter Polymorphism in the Monocyte Chemoattractant Protein-1 (MCP-1) Gene with Type 2 Diabetes and Coronary Artery Disease Genetic Testing and Molecular Biomarkers. ,vol. 17, pp. 750- 755 ,(2013) , 10.1089/GTMB.2013.0227
Jana Petrkova, Marian Bernadic, Thomas Buckingham, Martin Petrek, Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population Clinica Chimica Acta. ,vol. 392, pp. 71- 72 ,(2008) , 10.1016/J.CCA.2008.03.001
Pantelis G Bagos, A Unification of Multivariate Methods for Meta-Analysis of Genetic Association Studies Statistical Applications in Genetics and Molecular Biology. ,vol. 7, pp. 1- 35 ,(2008) , 10.2202/1544-6115.1408
Isabelle TMN Daissormont, Adriaan O Kraaijeveld, Erik AL Biessen, Chemokines as therapeutic targets for atherosclerotic plaque destabilization and rupture Future Cardiology. ,vol. 5, pp. 273- 284 ,(2009) , 10.2217/FCA.09.4
Ammarin Thakkinstian, John R. Thompson, Cosetta Minelli, John Attia, Choosing between per-genotype, per-allele, and trend approaches for initial detection of gene–disease association Journal of Applied Statistics. ,vol. 36, pp. 633- 646 ,(2009) , 10.1080/02664760802484990
Brad H. Rovin, Ling Lu, Ramesh Saxena, A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression. Biochemical and Biophysical Research Communications. ,vol. 259, pp. 344- 348 ,(1999) , 10.1006/BBRC.1999.0796
Elias Zintzaras, The Generalized Odds Ratio as a Measure of Genetic Risk Effect in the Analysis and Meta-Analysis of Association Studies Statistical Applications in Genetics and Molecular Biology. ,vol. 9, pp. 1- 14 ,(2010) , 10.2202/1544-6115.1542