Novel avenues in immunotherapies for colorectal cancer
作者： Iris N. Pardieck , Priscilla A. Jawahier , Marloes Swets , Cornelis J.H. van de Velde , Peter J.K. Kuppen
DOI: 10.1586/17474124.2016.1122522
关键词: Tumor microenvironment 、 Cancer research 、 Medicine 、 Cancer 、 Immunology 、 Cancer immunotherapy 、 Immunotherapy 、 Immune control 、 Colorectal cancer 、 Tumor growth 、 Immune system
摘要: Since it is known that the immune system affects tumor growth, has been studied if immunotherapy can be developed to combat cancer. While some successes have claimed, increasing knowledge on tumor-immune interactions has, however, also shown limitations of this approach. Tumors may show selective outgrowth cells escaped from control. Escape variants arise spontaneously due genetically instable nature cells. This one most obvious cancer immunotherapy. However, new therapies are becoming available, designed respond escape.
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