Determinants of Neutrophil Adhesion Following Ischemia

摘要: Inflammation describes a sequence of events that constitute the host response to foreign invasion and subsequent reactions are targeted at repair restoration normal physiology. While this process was initially thought be triggered by bacteria, it is now apparent many stimuli including tissue ischemia will initiate inflammatory possibly lead untoward results. Acute in heart or brain itself result significant morbidity mortality while other organs its effects may more subtle. Superimposed upon direct indirect results inflammation. This later become inappropriately intense generalized, leading severe unanticipated injury. Thus elective surgical procedures cause transient minor unmeasurable Following trauma clinical settings prolonged low flow, injury occur. In addition ischemic injury, reperfusion these tissues then an additional which mediated cells, complement, cytokines, products neutrophil oxidative metabolism granule release.