作者: F M Fouad-Tarazi , P R Liebson
DOI: 10.1161/01.HYP.9.2_PT_2.II65
关键词: Trimazosin 、 Medicine 、 Captopril 、 Reserpine 、 Methyldopa 、 Muscle hypertrophy 、 Hydralazine 、 Left ventricular hypertrophy 、 Cardiology 、 Internal medicine 、 Enalapril
摘要: The availability of echocardiography has allowed direct determinations left ventricular wall thickness and calculation mass. As a result, the past decade witnessed remarkable evolution in our understanding structural changes heart. Moreover, cardiac hypertrophy was found to be reversible by some forms therapy. In general, reduction mass became evident after 8 12 weeks antihypertensive Sympatholytics (including methyldopa reserpine), converting enzyme inhibitors (captopril enalapril), calcium entry blockers led significant regression hypertrophy. On other hand, arteriolar vasodilators (hydralazine, trimazosin, minoxidil) were not associated with despite adequate blood pressure control. Finally, data regarding diuretics beta-blockers are controversial. These differences results among various drugs reflect multiplicity factors modulating