"Not so immediate" hypersensitivity--the danger of biphasic anaphylactic reactions.

作者: E Brazil , A F MacNamara

DOI: 10.1136/EMJ.15.4.252

关键词: AnesthesiaEpinephrineAnaphylactic reactionAfter treatmentAnaphylactic reactionsRetrospective reviewAnaphylaxisCase noteRetrospective cohort studyMedicine

摘要: OBJECTIVE: To assess how commonly clinically significant biphasic anaphylactic reactions occur after apparently successful treatment of an reaction. Cases were analysed to determine whether there any markers that would allow early identification patients who subsequently develop a response. METHOD: Retrospective review case notes 34 admitted for observation reaction had required with adrenaline. RESULTS: Six (18%) reactions. No clinical features on initial presentation identified those likely have These however significantly more adrenaline ameliorate their symptoms (p = 0.03) compared having simple uniphasic CONCLUSIONS: Biphasic frequently. There are no require higher doses control and this should be considered marker may results confirm all being discharged acute must made aware the risk second phase response apparent resolution.

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