Mutant KRAS is a druggable target for pancreatic cancer
作者： E. Zorde Khvalevsky , R. Gabai , I. H. Rachmut , E. Horwitz , Z. Brunschwig
关键词: Cancer research 、 Pancreatic cancer 、 In vivo 、 KRAS 、 Oncogene 、 Immunology 、 Gene silencing 、 Targeted therapy 、 SiG12D LODER 、 Genetic enhancement 、 Biology
摘要: … and prolonged delivery of siRNA. Our results show that the siRNA targeted against KRAS mutations with a local prolonged release system knocks down KRAS expression in vitro and in …
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