Optical Coherence Tomography in the Management of Skull Base Fibrous Dysplasia with Optic Nerve Involvement.

摘要: Background Fibrous dysplasia (FD) of the skull base can manifest with optic nerve compression. As most patients initially do not experience vision loss, controversy exists whether to proceed prophylactic surgical decompression or elect for conservative observation. Optical coherence tomography (OCT), a physiologic imaging modality widely used assess condition retinal fiber layer (RNFL), has been useful in monitoring compressive tumors on nerve. This study evaluated potential use OCT management fibrous and involvement. Methods Six suspected compression who underwent as part neuro-ophthalmic examination were reviewed over 2-year period. Patient records visual measures, notably presence neuropathy, radiographic measures computed tomography. Measures compared by age-adjusted RNFL thickness (above below fifth percentile) imaging. Results Two found have mild neuropathy 1 eye each. Three 12 eyes fell percentile thickness. Presence was associated abnormal but (P = 0.45). Conclusions Abnormal measured better predicted than alone. may be valuable monitor development during periods watchful waiting.