The relationship between the dopaminergic system and depressive symptoms in cervical dystonia

作者: E. Zoons , M. A. J. Tijssen , Y. E. M. Dreissen , J. D. Speelman , M. Smit

DOI: 10.1007/S00259-017-3664-X

关键词: DopaminergicReceptorDopaminePathophysiologyInternal medicineEndocrinologyDepressive symptomsDepression (differential diagnoses)Cervical dystoniaAnesthesiaDopamine transporterMedicine

摘要: Purpose Cervical dystonia (CD) is associated with tremor/jerks (50%) and psychiatric complaints (17–70%). The dopaminergic system has been implicated in the pathophysiology of CD animal imaging studies. Dopamine may be related to motor as well non-motor symptoms CD. reduced striatal dopamine D2/3 (D2/3) receptor increased transporter (DAT) binding. There are differences between patients without jerks/tremor symptoms.

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