A fluorescence-enhanced probe for rapid detection of formaldehyde and its application for cell imaging

作者: Feng Wu , Yue Zhang , Lei Huang , Dan Xu , Hongying Wang

DOI: 10.1039/C7AY01786C

关键词: ChemistryFormaldehydeAnthraceneCellAldimineAnalytical chemistryCell membraneBiophysicsCondensation reactionFluorescenceRapid detection

摘要: A simple anthracene carboxyimide-based fluorescent probe has been readily developed for the detection of toxic formaldehyde (FA). The probe displays a remarkable fluorescence turn-on response towards FA based on the aldimine condensation reaction, which was confirmed by the HR-MS spectrum. The probe can quantitatively determine the level of FA with high selectivity and fast response (within 3 min). Furthermore, cell staining experiments indicate that the probe was cell membrane permeable and could be used for imaging FA in living …

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