High-Resolution Peripheral Quantitative Computed Tomography for the Assessment of Bone Strength and Structure: A Review by the Canadian Bone Strength Working Group
作者： Angela M. Cheung , Jonathan D. Adachi , David A. Hanley , David L. Kendler , K. Shawn Davison
DOI: 10.1007/S11914-013-0140-9
关键词: High resolution 、 Bone strength 、 Nuclear medicine 、 Imaging Tool 、 Bone mineral 、 Peripheral 、 Quantitative computed tomography 、 Tomography 、 Bone density 、 Computer science
摘要: Bone structure is an integral determinant of bone strength. The availability high resolution peripheral quantitative computed tomography (HR-pQCT) has made it possible to measure three-dimensional microarchitecture and volumetric mineral density in vivo, with accuracy previously unachievable relatively low-dose radiation. Recent studies using this novel imaging tool have increased our understanding age-related changes sex differences microarchitecture, as well the effect different pharmacological therapies. One advantage use finite element analysis modelling non-invasively estimate strength predict fractures reconstructed images. In paper, we describe strengths limitations HR-pQCT review clinical tool.
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