Microarchitectural Abnormalities Are More Severe in Postmenopausal Women with Vertebral Compared to Nonvertebral Fractures

摘要: Background: Abnormal bone microarchitecture predisposes postmenopausal women to fragility fractures. Whether with vertebral fractures have worse than those nonvertebral is unknown. Methods: Postmenopausal a history of low trauma fracture (n = 30) and 73) controls 120) had areal mineral density lumbar spine, total hip, femoral neck, 1/3 radius, ultradistal radius measured by dual-energy x-ray absorptiometry. Trabecular cortical volumetric were high-resolution peripheral quantitative computed tomography the distal tibia. Finite element analysis estimated whole stiffness. Results: Mean age subjects was 68 ± 7 yr. Groups similar respect age, race, body mass index. T-scores did not differ from at any site except (vertebral fracture, 0.6 sd lower; 0....