Non-pathogenic serotype 4 fowl adenovirus (fadv-4) and viral vector thereof

作者: Éva Nagy , Davor Ojkic , Helena Grgic , Bryan Griffin

DOI:

关键词: VirologyNucleic acid sequenceAntigenSerotypeTiterFowl adenovirusBiologyViral vector

摘要: A high level replication fowl adenovirus (FAdV) isolate capable of reaching a viral titer at least 3 log 10 is described. Said FAdV non-pathogenic strain serotype 4, identified as FAdV-4 ON1. Additionally, the present disclosure also provides vector comprising adenovirus, which has inserted an exogenous nucleotide sequence coding for one antigenic site disease concern, well method obtaining said and immunogenic composition same.

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