Consequences of Abdominal Adiposity within the Metabolic Syndrome Paradigm in Black People of African Ancestry

作者: Trudy Gaillard

DOI: 10.3390/JCM3030897

关键词: Internal medicineInsulin resistanceType 2 diabetesAbdominal obesityDyslipidemiaPhysiologyEthnic groupMetabolic syndromeObesityBeta-cell dysfunctionEndocrinologyMedicine

摘要: The metabolic syndrome (MetS) is a constellation of risk factors that are associated with increased risks for coronary heart disease and type 2 diabetes. Although the cause unknown, abdominal adiposity considered underpinning these alterations. Hence, contributes to dyslipidemia, hyperglycemia, beta cell dysfunction, insulin resistance, hypertension inflammation. role in causation alterations lead clinical expression MetS has become focus active research. In addition, there ethnic/racial differences manifestation MetS. Therefore, this current review to: (1) explore consequences obesity within paradigm; (2) discuss impact ethnicity/race on Black People African Ancestry (PAA).

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