Umbilical cord asymmetric dimethylarginine levels and ultrasound assessment of carotid arteries in neonates born small for gestational age

作者: Dilek Dilli , Elif Ozkan , Mehmet Burak Ozkan , Banu Aydin , Ahmet Özyazici

DOI: 10.1080/14767058.2016.1176136

关键词: Internal medicineProspective cohort studySmall for gestational ageUmbilical cordObstetricsAsymmetric dimethylargininePregnancyCase-control studyGestational ageCardiologyMedicineVascular resistance

摘要: AbstractBackground: To examine asymmetric dimethylarginine (ADMA) level as an endothelial function parameter in addition to ultrasonographic evaluation of carotid arteries babies born small for gestational age (SGA).Methods: Twenty-six neonates SGA and 34 appropriate (AGA) controls were included the study. The serum levels ADMA measured. Intima-media thickness (cIMT) resistive index (cRI) both determined by ultrasonography.Results: mean was higher compared AGAs (16 267.7 ± 6050 versus 12 810.2 ± 3302 ng/L; p = 0.01). cIMT (0.34 ± 0.02 0.31 ± 0.03 mm; p = 0.001) cRI (0.66 ± 0.07 0.61 ± 0.04, p = 0.003) also SGAs. Serum positively correlated (r = 0.41, p = 0.001). Although there a weak correlation between (r = 0.26, p = 0.04), no found (r = 0.17, p = 0.18).Conclusio...

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