Is asymmetric dimethylarginine associated with being born small and large for gestational age
作者： Valentina Chiavaroli , Laura Diesse , Tommaso de Giorgis , Cosimo Giannini , Maria Loredana Marcovecchio
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摘要: Abstract Low and high birth weights have been linked to increased susceptibility cardiovascular metabolic alterations. However, the natural history of cardiometabolic disturbances in children born small (SGA) large (LGA) for gestational age is still unclear no reliable biomarker risk has definitively identified these subjects. Interestingly, asymmetric dimethylarginine (ADMA), antagonist nitric oxide (NO) production, recognized as novel marker able identify subjects at higher health disturbances. Despite well-described role ADMA a predictor degenerative disease adults, its potential application pediatrics, specifically SGA LGA children, not explored only few data preterm infants newborns are available. Therefore, we investigated alterations circulating NO levels compared with those appropriate (AGA) age. Of no...
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