Sleepers versus nonsleepers: another twist to the dipper/nondipper concept.

摘要: There is growing evidence that an elevated nocturnal blood pressure associated with adverse cardiovascular outcome. In the Dublin Outcome Study, for each 10-mm Hg increase in mean nighttime systolic pressure, mortality risk increased by 21%.1 At present, ambulatory measurement only technique permits close examination of circadian profile and identification patterns may be risk. Much happens to system at nighttime, especially relation pressure. The pressure–nocturnal hypertension, hypotension, dipping nondipping, reverse dipping, autonomic failure–have been largely ignored clinical practice. Many studies evaluating morbidity status have supported concept a diminished fall worse prognosis.2 However, despite compelling changes hold many secrets that, if unlocked, might benefit management there has reluctance focus on both clinically hypertension research.3 The period 24-hour profile, which surprisingly complex, can divided into number windows discrete phenomena occur. These are retiring (or perhaps more aptly named vesperal) window, basal) window during sleep most likely, preawakening matinal) precedes rising. normal individual decline vesperal from daytime levels reach plateau basal (the “dipping” pattern), modest rise matinal regain pressure.4 hypertensive patients …