Adenoid cystic carcinoma of the larynx: a 40-year experience.
作者： Roger V. Moukarbel , David P. Goldstein , Brian O'Sullivan , Patrick J. Gullane , Dale H. Brown
DOI: 10.1002/HED.20802
关键词: Larynx 、 Medicine 、 Laryngeal Adenoid Cystic Carcinoma 、 Carcinoma 、 Retrospective cohort study 、 Subglottis 、 Regional Disease 、 Rare disease 、 Surgery 、 Adenoid cystic carcinoma
摘要: Background Laryngeal adenoid cystic carcinoma (ACC) is a rare disease. We reviewed our experience at the Princess Margaret Hospital (PMH) with its treatment. Methods This retrospective chart review of 15 cases treated PMH between 1963 and 2005. Results The mean age was 48.6 years. There no sex predilection. The subglottis most common subsite involved. Only 2 patients had regional metastasis. Local or recurrence noted in 5 (33.3%). distant metastasis rate 66.7% involved lungs. median follow-up time 6.9 5- 10-year overall disease-specific survival rates were 64% 46%, 69% 49%, respectively. Conclusion Laryngeal ACC disease high recurrence. Its management should emphasize maximizing local control by surgery followed radiotherapy failure eventually dictating survival. © 2008 Wiley Periodicals, Inc. Head Neck,
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