Prevention of mother‐to‐child transmission of HIV in Denmark, 1994–2008

摘要: Objectives The aim of this study was to describe trends in the management pregnancies HIV-infected women and their outcomes over a 14-year period Denmark on national basis. Methods retrospective cohort all giving birth one or more children between 1 June 1994 30 2008. Results We identified 210 with 255 pregnancies, ranging from 7 per year 1995 39 2006. Thirty cent were Caucasian 51% Black African. Knowledge HIV status before pregnancy increased 8% (four 49) 1994–1999 80% (164 206) 2000–2008. Only 29% (53 183) chose consult an infectious disease specialist when planning pregnancy, while 14% (27 199) received assistance fertility. The proportion antiretroviral therapy (ART) 76% (37 98% (201 Vaginal deliveries ranged 0 2003 35% 2007. Mother-to-child transmission (MTCT) decreased 10.4% 0.5% All HIV-positive child diagnosed during after delivery did not receive prophylactic ART. Conclusions annual number fivefold substantial changes seen. No woman treated according guidelines, i.e. ART week 22, intravenous zidovudine (ZDV) labour, neonatal ZDV for 4 6 weeks no breastfeeding, transmitted her child.