Carcinogen-specific mutation and amplification of Ha- ras during mouse skin carcinogenesis
作者： Miguel Quintanilla , Ken Brown , Martin Ramsden , Allan Balmain
DOI: 10.1038/322078A0
关键词: Methylnitronitrosoguanidine 、 Point mutation 、 Gene 、 Gene duplication 、 Molecular biology 、 Transversion 、 DNA damage 、 Mutation 、 Carcinogenesis 、 Biology
摘要: … Cellular proto-oncogenes can be activated by both point mutations and chromosomal translocations, suggesting that there may be a direct link between exposure to agents which …
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