Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient
作者： E Santos , D Martin-Zanca , E. Reddy , M. Pierotti , G Della Porta
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摘要: … of the six possible single point mutations that can activate the … Moreover, we have established that a single point mutation … The absence of this DNA fragment in NIH/3T3 transformants …
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T Y Shih, M O Weeks, H A Young, E M Scolnick, p21 of Kirsten murine sarcoma virus is thermolabile in a viral mutant temperature sensitive for the maintenance of transformation. Journal of Virology. ,vol. 31, pp. 546- 546 ,(1979) , 10.1128/JVI.31.2.546-546.1979
Elizabeth Taparowsky, Kenji Shimizu, Mitchell Goldfarb, Michael Wigler, Structure and activation of the human N-ras gene Cell. ,vol. 34, pp. 581- 586 ,(1983) , 10.1016/0092-8674(83)90390-2
Ueli Schibler, Toni Wyler, Otto Hagenbüchle, Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution Journal of Molecular Biology. ,vol. 94, pp. 503- 517 ,(1975) , 10.1016/0022-2836(75)90217-X
A. Feinberg, B Vogelstein, M. Droller, S. Baylin, B. Nelkin, Mutation Affecting the 12th Amino Acid of the c-Ha-ras Oncogene Product Occurs Infrequently in Human Cancer Science. ,vol. 220, pp. 1175- 1177 ,(1983) , 10.1126/SCIENCE.6304875
Mitchell Goldfarb, Kenji Shimizu, Manuel Perucho, Michael Wigler, Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells Nature. ,vol. 296, pp. 404- 409 ,(1982) , 10.1038/296404A0
E. Stanbridge, C. Der, C. Doersen, R. Nishimi, D. Peehl, B. Weissman, J. Wilkinson, Human cell hybrids: analysis of transformation and tumorigenicity Science. ,vol. 215, pp. 252- 259 ,(1982) , 10.1126/SCIENCE.7053574
A. M. Maxam, W. Gilbert, A new method for sequencing DNA Proceedings of the National Academy of Sciences of the United States of America. ,vol. 74, pp. 560- 564 ,(1977) , 10.1073/PNAS.74.2.560
E. Premkumar Reddy, Roberta K. Reynolds, Eugenio Santos, Mariano Barbacid, A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene Nature. ,vol. 300, pp. 149- 152 ,(1982) , 10.1038/300149A0
HENRY HARRIS, O. J. MILLER, G. KLEIN, P. WORST, T. TACHIBANA, Suppression of Malignancy by Cell Fusion Nature. ,vol. 223, pp. 363- 368 ,(1969) , 10.1038/223363A0
G. Cooper, Cellular transforming genes Science. ,vol. 217, pp. 801- 806 ,(1982) , 10.1126/SCIENCE.6285471