作者: MAUREENA A MURTAUGH , ANN M FERRIS , CONSTANCE M CAPACCHIONE , E.ALBERT REECE
DOI: 10.1016/S0002-8223(98)00147-3
关键词: Diabetes mellitus 、 Insulin 、 Analysis of variance 、 Endocrinology 、 Type 1 diabetes 、 Internal medicine 、 Postprandial 、 Metabolic control analysis 、 Lactation 、 Obstetrics 、 Medicine 、 Glycated hemoglobin
摘要: Abstract Objective To describe glycemia and insulin administration in lactating women with type 1 diabetes compare their energy intake, lactation onset, postpartum weight to without diabetes. Design A prospective observational study conducted at 2, 3, 6, 14, 42, 84 days postpartum. Insulin dosage glucose levels after fasting 80 110 minutes eating (by measuring capillary blood concentrations glycated hemoglobin [HbA 1c ] values) are described for Dietary weight, onset compared those the disease. Subjects/setting Fourteen 25 (control subjects) were recruited from private obstetrician offices high-risk prenatal clinics 3 major medical centers. Statistical analyses repeated-measures 2-factor analysis of variance was used determine group, time, interaction effects between control group 7, Results Seven breast-fed through postpartum, although they perceived later milk had postprandial hyperglycemia. Their HbA increased by 20%, confirming relative After adjustment prepregnancy consumed 7kcal fewer per kilogram day than subjects. Average dose returned 45.3±3.6U/d (least square means±standard error mean) week. Application Achieving desired metabolic during establishment is difficult. better understanding needs relationship needed. J Am Diet Assoc. 1998; 98: 642–648 .