Vasodilators: scorpion envenoming and the heart (an Indian experience).

摘要: Our aim was to assess clinically whether there any benefit in adding a single dose of sublingual nifedipine (a slow calcium channel blocker) prazosin the management cardiovascular manifestations envenoming by Indian red scorpion (Mesobuthus tamulus). A total 163 patients stung this species admitted hospital at Mahad between January 1991 and October 1993. Cardiovascular abnormalities were hypertension (59), whom 42 had bradycardia 17 tachycardia; pulmonary oedema (14), eight six hypotension; supraventricular tachycardia (eight), three hypotension one died. Of remaining patients, 78 demonstrated severe excruciating local pain site sting but no systemic involvement. Nineteen with given plus on admission, then alone repeated 6 hourly. Five massive life-threatening recovered after being intravenous sodium nitroprusside. Prazosin helped alleviate 52 victims. One patient deep coma, 12 hr sting, Eight victims whose blood pressure been controlled developed acute necessitating additional doses for recovery. Fifty-two treated did not develop drug appeared hasten In presence high pressure, tachycardia, murmur impending myocardial failure, contribute cardiopulmonary instability augment oxygen consumption. situation blockers should probably be avoided.