Analysis on interrelation between electroacupuncture-induced cumulative analgesic effect and hypothalamic cholinergic activities in chronic neuropathic pain rats

作者: Jun-ying Wang , Fan-ying Meng , Shu-ping Chen , Yong-hui Gao , Jun-ling Liu

DOI: 10.1007/S11655-012-1059-1

关键词: EndocrinologyZusanliAcetylcholineAcetylcholinesteraseCholine acetyltransferaseElectroacupunctureMuscarinic acetylcholine receptor M1MedicineCholinergicMuscarinic acetylcholine receptorInternal medicine

摘要: Objective To observe the effects of repeated electroacupuncture (EA) Zusanli (ST36)- Yanglingquan (GB34) on hypothalamic acetylcholinesterase (AchE) and vesicular acetylcholine (ACh) transporter (VAChT) activities choline acetyltransferase (ChAT) mRNA muscarinic M1 receptor (M1R) expression in chronic constrictive injury (CCI) and/or ovariectomy (OVX) rats so as to reveal its underlying mechanism cumulative analgesia.

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