DPPH radical scavenging and xanthine oxidase inhibitory activity of Terminalia macroptera leaves.
作者： Anh Thu Pham , Karl Egil Malterud , Berit Smestad Paulsen , Drissa Diallo , Helle Wangensteen
DOI: 10.1177/1934578X1100600819
关键词: Chebulagic acid 、 Chemistry 、 Chebulinic acid 、 Chebulic acid 、 Traditional medicine 、 Corilagin 、 Methyl gallate 、 Terminalia macroptera 、 Xanthine oxidase inhibitor 、 Xanthine oxidase
摘要: From a methanol extract of the leaves Malian medicinal tree Terminalia macroptera, cis-polyisoprene (1), chebulic acid trimethyl ester (2), methyl gallate (3), shikimic (4), corilagin (5), rutin (6), narcissin (7), chebulagic (8) and chebulinic (9), were isolated. Cispolyisoprene (1) was major non-polar constituent. The novel compound 2 showed high radical scavenging activity (IC50 4.7 microg/mL), but inactive as xanthine oxidase inhibitor. substituent crude extract, substance 5, scavenger effect 2.7 microg/mL) weak inhibition ca 105 microg/mL). antioxidant effects some substances identified in this study may to extent explain medical use West Africa.
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