Vanillic Acid 4-O-β-D-(6′-O-Galloyl) Glucopyranoside and Other Constituents from the Bark of Terminalia macroptera Guill. Et Perr

作者: Jürgen Conrad , Bernhard Vogler , Iris Klaiber , Sabine Reeb , Jan-Hinrich Guse

DOI: 10.1080/10575630108041255

关键词: BarkVanillic acidAntimicrobialTriterpeneStereochemistryChemistryTerminalia macropteraGlucosideCombretaceaeBacillus subtilis

摘要: Abstract A new phenolic glucoside gallate, vanillic acid 4-O-β-D-(6′-O-galloyl) glucopyranoside (1) was isolated from the bark of Terminalia macroptera Guill.et Perr., together with 3,3′,4′-tri-O-methylellagic (2) and two triterpene glucopyranosyl esters, 24-deoxy-sericoside (3) chebuloside II (4). Compounds 2-4 not described previously for this plant, showed antimicrobial activities against Bacillus subtilis, while 3 4 possessed haemolytic properties. In both assays 1 found to be inactive.

参考文章(7)
Zhou Xiao-Hong, Ryoji Kasai, Kazuhiro Ohtani, Osamu Tanaka, Nie Rui-Lin, Yang Chong-Ren, Zhou Jun, Kazuo Yamasaki, Oleanane and ursane glucosides from Rubus species Phytochemistry. ,vol. 31, pp. 3642- 3644 ,(1992) , 10.1016/0031-9422(92)83747-M
Akiyo Sakushima, Maksut Coşkun, Takashi Maoka, Hydroxybenzoic acids from Boreava orientalis Phytochemistry. ,vol. 40, pp. 257- 261 ,(1995) , 10.1016/0031-9422(95)00059-G
George R. Pettit, Gordon M. Cragg, Sheo Bux Singh, Antineoplastic agents, 122. Constituents of Combretum caffrum. Journal of Natural Products. ,vol. 50, pp. 386- 391 ,(1987) , 10.1021/NP50051A008
Jürgen Conrad, Bernhard Vogler, Iris Klaiber, Gudrun Roos, Ulrich Walter, Wolfgang Kraus, Two triterpene esters from Terminalia macroptera bark Phytochemistry. ,vol. 48, pp. 647- 650 ,(1998) , 10.1016/S0031-9422(98)00154-X
Asish P. Kundu, Shashi B. Mahato, Triterpenoids and their glycosides from Terminalia chebula. Phytochemistry. ,vol. 32, pp. 999- 1002 ,(1993) , 10.1016/0031-9422(93)85243-K
Matthias O. Hamburger, Geoffrey A. Cordell, A direct bioautographic tlc assay for compounds possessing antibacterial activity. Journal of Natural Products. ,vol. 50, pp. 19- 22 ,(1987) , 10.1021/NP50049A003