The Effect of Cytokines on the Proliferation and Migration of Bovine Meniscal Cells
作者： Madhu M. Bhargava , Erik T. Attia , George A. C. Murrell , Martin M. Dolan , Russell F. Warren
DOI: 10.1177/03635465990270051601
关键词: Cell biology 、 In vitro 、 Endocrinology 、 Cell 、 Epidermal growth factor 、 Cell migration 、 Medicine 、 Cytokine 、 Hepatocyte growth factor 、 Internal medicine 、 Growth factor 、 DNA synthesis 、 Physical Therapy, Sports Therapy and Rehabilitation 、 Orthopedics and Sports Medicine
摘要: We determined the effect of cytokines on proliferation and migration cells isolated from inner-third (white-white), middle-third (red-white), outer-third (red-red) regions bovine meniscus. Cells outer, or peripheral, region meniscus exhibited higher DNA synthesis in presence 10% serum compared with inner central regions. Recombinant human platelet-derived growth factor-AB, hepatocyte factor/scatter factor, bone morphogenic protein-2 stimulated all meniscal a dose-dependent manner, two- to threefold maximal stimulation at 10 ng/ml. Cell was also by addition cytokines. Platelet-derived factor caused an increase derived three zones, while interleukin-1 selectively outer-zone cells. Epidermal much less effective outer zones 40% 50%, insulin-like factor-1 middle zone 50%. The identification that stimulate both may provide new tools for modulation healing.
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sci-hub.se 参考文章(34)
Macconaill Ma, The Function of Intra-Articular Fibrocartilages, with Special Reference to the Knee and Inferior Radio-Ulnar Joints Journal of Anatomy. ,vol. 66, pp. 210- 227 ,(1932)
Scott A. Rodeo, Russell F. Warren, Meniscal repair using the outside-to-inside technique. Clinics in Sports Medicine. ,vol. 15, pp. 469- 481 ,(1996) , 10.1016/S0278-5919(20)30106-X
P. M. Henson, R. A. F. Clark, The Molecular and Cellular Biology of Wound Repair ,(1995)
L.A. Boyan, G. Bhargava, F. Nishimura, R. Orman, R. Price, V.P. Terranova, Mitogenic and Chemotactic Responses of Human Periodontal Ligament Cells to the Different Isoforms of Platelet-derived Growth Factor Journal of Dental Research. ,vol. 73, pp. 1593- 1600 ,(1994) , 10.1177/00220345940730100301
U Jorgensen, S Sonne-Holm, F Lauridsen, A Rosenklint, Long-term follow-up of meniscectomy in athletes. A prospective longitudinal study Journal of Bone and Joint Surgery-british Volume. ,vol. 69, pp. 80- 83 ,(1987) , 10.1302/0301-620X.69B1.3818740
Jun Hashimoto, Masahiro Kurosaka, Shinichi Yoshiya, Kazushi Hirohata, Meniscal repair using fibrin sealant and endothelial cell growth factor. An experimental study in dogs. American Journal of Sports Medicine. ,vol. 20, pp. 537- 541 ,(1992) , 10.1177/036354659202000509
C. C. Schmidt, H. I. Georgescu, C. K. Kwoh, G. L. Blomstrom, C. P. Engle, L. A. Larkin, C. H. Evans, S. L-Y. Woo, Effect of growth factors on the proliferation of fibroblasts from the medial collateral and anterior cruciate ligaments Journal of Orthopaedic Research. ,vol. 13, pp. 184- 190 ,(1995) , 10.1002/JOR.1100130206
T Takebayashi, M Iwamoto, A Jikko, T Matsumura, M Enomoto-Iwamoto, F Myoukai, E Koyama, T Yamaai, K Matsumoto, T Nakamura, Hepatocyte growth factor/scatter factor modulates cell motility, proliferation, and proteoglycan synthesis of chondrocytes. Journal of Cell Biology. ,vol. 129, pp. 1411- 1419 ,(1995) , 10.1083/JCB.129.5.1411
Arkady S. Voloshin, Josef Wosk, Shock absorption of meniscectomized and painful knees: a comparative in vivo study. Journal of Biomedical Engineering. ,vol. 5, pp. 157- 161 ,(1983) , 10.1016/0141-5425(83)90036-5
D. S. Grant, H. K. Kleinman, I. D. Goldberg, M. M. Bhargava, B. J. Nickoloff, J. L. Kinsella, P. Polverini, E. M. Rosen, Scatter factor induces blood vessel formation in vivo. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 1937- 1941 ,(1993) , 10.1073/PNAS.90.5.1937